Product overview
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Background
EPHA1 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis.
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Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1: 500 - 1: 2000 |
| IHC | 1: 100 - 1: 300 |
| IF | 1: 200 - 1: 1000 |
| ELISA | 1: 20000 |
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