Fibulin-5 Polyclonal Antibody

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Home > Product > Antibody > Fibulin-5 Polyclonal Antibody

Fibulin-5 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

Fibulin-5 Antibody

Code

BT-AP03242

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human FBLN5. AA range:171-220

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Fibulin-5 encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

50180

Gene ID

Human: 10516; Mouse: 23876; Rat: 29158

Synonyms

FBLN5; DANCE; Fibulin-5; FIBL-5; Developmental arteries and neural crest EGF-like protein; Dance; Urine p50 protein; UP50

Research area

Signal Transduction

Target protein

FBLN5

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 5000

Images

Western Blot analysis of various cells using Fibulin-5 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of L929 cells using Fibulin-5 Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from NIH/3T3 cells, using FBLN5 Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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