Product overview
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Background
FZD3 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. The function of Frizzled-3 is unknown, although it may play a role in mammalian hair follicle development. Alternative splicing results in multiple transcript variants. FZD3 is a susceptibility locus for schizophrenia.
Uniprot accession
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Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| IHC-p | 1: 50 - 200 |
| ELISA | 1: 10000 - 20000 |
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