GCSc-Gamma Polyclonal Antibody

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Home > Product > Antibody > GCSc-Gamma Polyclonal Antibody

GCSc-Gamma Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

GCSc-gamma Antibody

Code

BT-AP03520

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human GCSc-gamma. AA range:266-315

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. GCLC encodes Glutamate--cysteine ligase catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at GCLC have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

72766

Gene ID

Human: 2729; Mouse: 14629; Rat: 25283

Synonyms

GCLC; GLCL; GLCLC; Glutamate--cysteine ligase catalytic subunit; GCS heavy chain; Gamma-ECS; Gamma-glutamylcysteine synthetase

Research area

Signal Transduction; Metabolism

Target protein

GCLC

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western blot analysis of lysate from A549 cells, using GCSc-γ antibody.

Western Blot analysis of various cells using GCSc-γ Polyclonal Antibody

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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