gp91-phox Polyclonal Antibody

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Home > Product > Antibody > gp91-phox Polyclonal Antibody

gp91-phox Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

gp91-phox Antibody

Code

BT-AP03658

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human gp91-phox. AA range:453-502

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Uniprot accession

Human:;Mouse:;

Molecular weight

65336

Gene ID

Human: 1536; Mouse: 13058

Synonyms

CYBB; NOX2; Cytochrome b-245 heavy chain; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome

Research area

Immunology

Target protein

CYBB

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western Blot analysis of various cells using gp91-phox Polyclonal Antibody diluted at 1:1000

Western Blot analysis of AD293 RAW using gp91-phox Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysate from HT29 cells, using gp91-phox antibody.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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