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Home > Product > Antibody > HDAC8 Polyclonal Antibody

HDAC8 Polyclonal Antibody

HDAC8 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-p, ELISA

Product overview

Full product name

HDAC8 Antibody

Code

BT-AP03928

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC8. AA range:5-54

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 8 encoded by HDAC8 belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for HDAC8.

Uniprot accession

Molecular weight

41758

Gene ID

Human: 55869; Mouse: 70315; Rat: 1.00912e+008

Synonyms

HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

Research area

Epigenetics and Nuclear Signaling

Target protein

HDAC8

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
ELISA 1: 20000

Images

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using HDAC8 Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using HDAC8 Polyclonal Antibody diluted at 1:1000
Western Blot analysis of 293-UV cells using HDAC8 Polyclonal Antibody diluted at 1:1000
Western blot analysis of lysates from NIH/3T3, HeLa, and Jurkat cells, , using HDAC8 Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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