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Home > Product > Antibody > Histone deacetylase 6 Polyclonal Antibody

Histone deacetylase 6 Polyclonal Antibody

Histone deacetylase 6 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Histone deacetylase 6 Antibody

Code

BT-AP03986

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human HDAC6. AA range:1166-1215

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 6 encoded by HDAC6 belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription.

Uniprot accession

Molecular weight

131431

Gene ID

Human: 10013; Mouse: 15185

Synonyms

HDAC6; KIAA0901; JM21; Histone deacetylase 6; HD6

Research area

Epigenetics and Nuclear Signaling

Target protein

HDAC6

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
IF 1: 200 - 1: 1000
ELISA 1: 20000

Images

Western Blot analysis of MCF7 cells using Histone deacetylase 6 Polyclonal Antibody diluted at 1:2000
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using HDAC6 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HeLa cells, using HDAC6 Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using Histone deacetylase 6 Polyclonal Antibody diluted at 1:2000

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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