Histone H2A Polyclonal Antibody

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Home > Product > Antibody > Histone H2A Polyclonal Antibody

Histone H2A Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, WB, ELISA

Product overview

Full product name

Histone H2A Antibody

Code

BT-AP03998

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Histone H2A. AA range:1-50

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFZ encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

51633

Gene ID

Human: 3015; Mouse: 51788; Rat: 58940

Synonyms

H2AFZ; H2AZ; Histone H2A.Z; H2A/z

Research area

Epigenetics and Nuclear Signaling

Target protein

H2AFZ

Recommended dilution

Application	Dilution
WB	1: 500 - 2000
ELISA	1: 5000
IHC	1: 100 - 1: 300

Images

Western blot analysis of lysates from DU145 cells, primary antibody was diluted at 1:1000, 4°over night

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Histone H2A Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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