IL-10R Alpha Polyclonal Antibody

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Home > Product > Antibody > IL-10R Alpha Polyclonal Antibody

IL-10R Alpha Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IF, ELISA

Product overview

Full product name

IL-10Ralpha Antibody

Code

BT-AP04431

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-10R alpha. AA range:462-511

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Interleukin-10 receptor subunit alpha encoded by IL10RA is a receptor for interleukin 10. Interleukin-10 receptor subunit alpha is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

62904

Gene ID

Human: 3587

Synonyms

IL10RA; IL10R; Interleukin-10 receptor subunit alpha; IL-10 receptor subunit alpha; IL-10R subunit alpha; IL-10RA; CDw210a; Interleukin-10 receptor subunit 1; IL-10R subunit 1; IL-10R1; CD antigen CD2

Research area

Immunology

Target protein

IL10RA

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IF	1: 200 - 1: 1000
ELISA	1: 10000

Images

Immunofluorescence analysis of HepG2 cells, using IL-10R alpha Antibody. The picture on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using IL-10Rα Polyclonal Antibody

Western blot analysis of lysates from HepG2 cells, treated with Na2VO3 0.3nM 40', using IL-10R alpha Antibody. The lane on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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