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Background
Cytokine receptor common subunit gamma encoded by IL2RG is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
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Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1: 500 - 1: 2000 |
| ELISA | 1: 20000 |
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