IL-4R Alpha Polyclonal Antibody

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Home > Product > Antibody > IL-4R Alpha Polyclonal Antibody

IL-4R Alpha Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: WB, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB, IF, ELISA

Product overview

Full product name

IL-4Ralpha Antibody

Code

BT-AP04506

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human IL-4R/CD124. AA range:463-512

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

IL4R encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. Interleukin-4 receptor subunit alpha also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection. Alternate splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

89658

Gene ID

Human: 3566; Mouse: 16190

Synonyms

IL4R; IL4RA; 582J2.1; Interleukin-4 receptor subunit alpha; IL-4 receptor subunit alpha; IL-4R subunit alpha; IL-4R-alpha; IL-4RA; CD antigen CD124

Research area

Immunology

Target protein

IL4R

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IF	1: 200 - 1: 1000
ELISA	1: 20000

Images

Western blot analysis of the lysates from HUVECcells using IL-4R/CD124 antibody.

Western blot analysis of mouse-kidney 293T lysis using IL-4Rα antibody. Antibody was diluted at 1:2000

Immunofluorescence analysis of A549 cells, using IL-4R/CD124 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from 293 cells, using IL-4R/CD124 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using IL-4Rα Polyclonal Antibody diluted at 1:2000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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