Full product name
IP3KA Antibody
Code
BT-AP04602
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IP3KA. AA range:396-445
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
Uniprot accession
Molecular weight
51009
Gene ID
Human: 3706; Mouse: 228550; Rat: 81677
Synonyms
ITPKA; Inositol-trisphosphate 3-kinase A; Inositol 1; 4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
Research area
Others
Target protein
ITPKA