Product overview
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IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Uniprot accession
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Recommended dilution
| Application | Dilution |
|---|---|
| WB | 1: 500 - 2000 |
| IHC-p | 1: 500 - 200 |
| ELISA | 1: 10000 - 20000 |
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