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Home > Product > Antibody > KV1.1 Polyclonal Antibody

KV1.1 Polyclonal Antibody

KV1.1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

KV1.1 Antibody

Code

BT-AP04904

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human KCNA1. AA range:256-305

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

KCNA1 encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. Potassium voltage-gated channel subfamily A member 1 has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Uniprot accession

Molecular weight

56542

Gene ID

Human: 3736; Mouse: 16485; Rat: 24520

Synonyms

KCNA1; Potassium voltage-gated channel subfamily A member 1; Voltage-gated K(+) channel HuKI; Voltage-gated potassium channel HBK1; Voltage-gated potassium channel subunit Kv1.1

Research area

Neuroscience

Target protein

KCNA1

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 10000

Images

Western Blot analysis of HeLa cells using KV1.1 Polyclonal Antibody diluted at 1:2000
Western blot analysis of lysates from HUVEC, MCF-7, and HeLa cells, using KCNA1 Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using KV1.1 Polyclonal Antibody diluted at 1:2000
Western blot analysis of the lysates from HepG2 cells using KCNA1 antibody.

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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