MDM2 Polyclonal Antibody

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Blood coagulation
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Home > Product > Antibody > MDM2 Polyclonal Antibody

MDM2 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: IHC-p, IF, WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: IHC-p, IF, WB, ELISA

Product overview

Full product name

MDM2 Antibody

Code

BT-AP05301

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human MDM2. AA range:151-200

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

MDM2 encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells.

Uniprot accession

Human:;Mouse:;

Molecular weight

55233

Gene ID

Human: 4193

Synonyms

MDM2; E3 ubiquitin-protein ligase Mdm2; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2

Research area

Cell Biology

Target protein

MDM2

Recommended dilution

Application	Dilution
WB	1: 500 - 2000
IF	1: 200 - 1: 1000
ELISA	1: 5000
IHC	1: 100 - 1: 300

Images

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using MDM2 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunofluorescence analysis of NIH/3T3 cells, using MDM2 Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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