MKP-5 Antibody

BT-AP05446

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from MKP-5 . at AA range: 330-410

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAP kinase superfamily, which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAP kinases, different tissue distribution and subcellular localization, and different modes of expression induction by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK. Alternative splicing results in multiple transcript variants.

Human: Q9Y6W6; Mouse: Q9ESS0;

52642

Human: 11221; Mouse: 63953

DUSP10; MKP5; Dual specificity protein phosphatase 10; Mitogen-activated protein kinase phosphatase 5; MAP kinase phosphatase 5; MKP-5

Signal Transduction

DUSP10