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Home > Product > Antibody > Nephrin Polyclonal Antibody

Nephrin Polyclonal Antibody

Nephrin Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC-p, ELISA

Product overview

Full product name

Nephrin Antibody

Code

BT-AP05888

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human Nephrin. AA range:843-892

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. NPHS1 is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.

Uniprot accession

Molecular weight

134742

Gene ID

Human: 4868; Mouse: 54631; Rat: 64563

Synonyms

NPHS1; NPHN; Nephrin; Renal glomerulus-specific cell adhesion receptor

Research area

Signal Transduction

Target protein

NPHS1

Recommended dilution

Application Dilution
IHC 1: 100 - 1: 300
ELISA 1: 40000

Images

Immunohistochemistry analysis of Nephrin antibody in paraffin-embedded human brain tissue.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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