NFKappaB-p100 Polyclonal Antibody

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Home > Product > Antibody > NFKappaB-p100 Polyclonal Antibody

NFKappaB-p100 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

NFkappaB-p100 Antibody

Code

BT-AP05973

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human NF-kappaB p100/p52. AA range:836-885

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

NFKB2 encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. Nuclear factor kappa B subunit 2 encoded by NFKB2 can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for NFKB2 on chromosome 18. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;

Molecular weight

96749

Gene ID

Human: 4791; Mouse: 18034

Synonyms

NFKB2; LYT10; Nuclear factor NF-kappa-B p100 subunit; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; Nuclear factor of kappa light polypeptide gene enhancer in B-cells

Research area

Cell Biology

Target protein

NFKB2

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 10000

Images

Western Blot analysis of various cells using NFκB-p100 Polyclonal Antibody diluted at 1:2000

Western blot analysis of lysates from RAW264.7 cells, using NF-kappaB p100/p52 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of KB K562 Hela 293T lysis using NFκB-p100 antibody. Antibody was diluted at 1:2000

Western Blot analysis of Jurkat cells using NFκB-p100 Polyclonal Antibody diluted at 1:2000

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using NF-kappaB p100/p52 Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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