Ob-R Polyclonal Antibody

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Home > Product > Antibody > Ob-R Polyclonal Antibody

Ob-R Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, ELISA

Product overview

Full product name

Ob-R Antibody

Code

BT-AP06323

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from Leptin receptor at AA range: 791-840

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Leptin receptor encoded by LEPR belongs to the gp130 family of cytokine receptors that are known to stimulate gene transcription via activation of cytosolic STAT proteins. This protein is a receptor for leptin (an adipocyte-specific hormone that regulates body weight), and is involved in the regulation of fat metabolism, as well as in a novel hematopoietic pathway that is required for normal lymphopoiesis. Mutations in this gene have been associated with obesity and pituitary dysfunction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. It is noteworthy that this gene and LEPROT gene (GeneID: 54741) share the same promoter and the first 2 exons, however, encode distinct proteins (PMID: 9207021).

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

132494

Gene ID

Human: 3953; Mouse: 16847; Rat: 24536

Synonyms

LEPR; DB; OBR; Leptin receptor; LEP-R; HuB219; OB receptor; OB-R; CD295

Research area

Signal Transduction

Target protein

LEPR

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000

Images

Western Blot analysis of HeLa, K562, MCF7 cells using Ob-R Polyclonal Antibody. Antibody was diluted at 1:1000. Secondary antibody was diluted at 1:20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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