p18 Polyclonal Antibody

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Home > Product > Antibody > p18 Polyclonal Antibody

p18 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Monkey

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Monkey

Applications: WB, IHC-p, ELISA

Product overview

Full product name

p18 Antibody

Code

BT-AP06747

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human p18 INK. AA range:111-160

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Cyclin dependent kinase inhibitor 2C encoded by CDKN2C is a member of the INK4 family of cyclin-dependent kinase inhibitors. Cyclin dependent kinase inhibitor 2C has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of CDKN2C was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of CDKN2C in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of CDKN2C, which encode an identical protein, have been reported.

Uniprot accession

Human:;Mouse:;

Molecular weight

18127

Gene ID

Human: 1031; Mouse: 12580

Synonyms

CDKN2C; CDKN6; Cyclin-dependent kinase 4 inhibitor C; Cyclin-dependent kinase 6 inhibitor; p18-INK4c; p18-INK6

Research area

Cell Biology

Target protein

CDKN2C

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC	1: 100 - 1: 300
ELISA	1: 20000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using p18 INK Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from COS7 cells, using p18 INK Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using p18 Polyclonal Antibody

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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