Perforin 1 Polyclonal Antibody

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Home > Product > Antibody > Perforin 1 Polyclonal Antibody

Perforin 1 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC, ELISA

Product overview

Full product name

Perforin 1 Antibody

Code

BT-AP07063

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human PRF1. AA range:451-500

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

The protein encoded by PRF1 (perforin 1) has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in PRF1 cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein.

Uniprot accession

Human:;Mouse:;

Molecular weight

61377

Gene ID

Human: 5551; Mouse: 18646

Synonyms

Perforin-1 (P1) (Cytolysin) (Lymphocyte pore-forming protein) (PFP)

Research area

Immunology

Target protein

Perforin-1

Recommended dilution

Application	Dilution
WB	1: 500 - 2000
IHC	1: 50 - 200
ELISA	1: 10000 - 20000

Images

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Western Blot analysis of Hela cells using Perforin 1 Polyclonal Antibody diluted at 1:500. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-kidney, antibody was diluted at 1:200

Immunohistochemical analysis of paraffin-embedded human-spleen, antibody was diluted at 1:200

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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