PGI2 synthase Polyclonal Antibody

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Home > Product > Antibody > PGI2 synthase Polyclonal Antibody

PGI2 synthase Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

PGI2 synthase Antibody

Code

BT-AP07100

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized peptide derived from the C-terminal region of human PGI2 synthase.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

PTGIS (prostaglandin I2 (prostacyclin) synthase) encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

57104

Gene ID

Human: 5740; Mouse: 19223; Rat: 25527

Synonyms

PTGIS; CYP8; CYP8A1; Prostacyclin synthase; Prostaglandin I2 synthase

Research area

Immunology

Target protein

PTGIS

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 40000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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