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Home > Product > Antibody > PKR Polyclonal Antibody

PKR Polyclonal Antibody

PKR Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

PKR Antibody

Code

BT-AP07245

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human PKR. AA range:413-462

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of eukaryotic translation initiation factor 2 alpha kinase 2 can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. Eukaryotic translation initiation factor 2 alpha kinase 2 encoded by EIF2AK2 is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for EIF2AK2.

Uniprot accession

Molecular weight

62094

Gene ID

Human: 5610

Synonyms

EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-depe

Research area

Signal Transduction

Target protein

EIF2AK2

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
IHC 1: 100 - 1: 300
ELISA 1: 20000

Images

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PKR Antibody. The picture on the right is blocked with the synthesized peptide.
Western Blot analysis of HeLa cells using PKR Polyclonal Antibody diluted at 1:2000
Western blot analysis of lysates from HeLa, using PKR Antibody. The lane on the right is blocked with the synthesized peptide.
Western Blot analysis of various cells using PKR Polyclonal Antibody diluted at 1:2000

Protocols

Customer reviews and Q&As

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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