PP2A-ABeta Polyclonal Antibody

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Home > Product > Antibody > PP2A-ABeta Polyclonal Antibody

PP2A-ABeta Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

PP2A-Abeta Antibody

Code

BT-AP07343

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human PPP2R1B. AA range:552-601

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

PPP2R1B encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. PPP2R1B encodes a beta isoform of the constant regulatory subunit A. Mutations in PPP2R1B have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

66214

Gene ID

Human: 5519; Mouse: 73699; Rat: 315648

Synonyms

PPP2R1B; Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform; PP2A subunit A isoform PR65-beta; PP2A subunit A isoform R1-beta

Research area

Signal Transduction

Target protein

PPP2R1B

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000
IHC-p	1: 50 - 300

Images

Western Blot analysis of various cells using PP2A-Aβ Polyclonal Antibody

Western blot analysis of the lysates from Jurkat cells using PPP2R1B antibody.

Western blot analysis of lysates from HeLa and Jurkat cells, using PPP2R1B Antibody. The lane on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PPP2R1B Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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