Full product name
PTPalpha Antibody
Code
BT-AP07504
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthesized peptide derived from PTPα . at AA range: 730-810
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
The protein encoded by PTPRA (protein tyrosine phosphatase, receptor type A) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of PTPRA, which encode two distinct isoforms, have been reported.
Uniprot accession
Molecular weight
90600
Gene ID
Human: 5786; Mouse: 19262
Synonyms
PTPRA; PTPA; PTPRL2; Receptor-type tyrosine-protein phosphatase alpha; Protein-tyrosine phosphatase alpha; R-PTP-alpha
Research area
Signal Transduction
Target protein
PTPRA
