PUMA Polyclonal Antibody

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Home > Product > Antibody > PUMA Polyclonal Antibody

PUMA Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, ELISA

Product overview

Full product name

PUMA Antibody

Code

BT-AP07510

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human PUMA. AA range:120-169

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

BBC3 encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. BCL2 binding component 3 cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, BBC3 is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

20532/14459

Gene ID

Human: 27113; Mouse: 170770; Rat: 317673

Synonyms

BBC3; PUMA; Bcl-2-binding component 3; JFY-1; p53 up-regulated modulator of apoptosis

Research area

Cell Biology

Target protein

BBC3

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 10000

Images

Western blot analysis of lysate from 293 cells treated with EGF, using PUMA antibody.

Western Blot analysis of various cells using PUMA Polyclonal Antibody

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

Custom quote | Bulk request

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