Full product name
Rad23B Antibody
Code
BT-AP07605
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RAD23B. AA range:1-50
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
RAD23 homolog B, nucleotide excision repair protein encoded by RAD23B is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). RAD23 homolog B, nucleotide excision repair protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. RAD23 homolog B, nucleotide excision repair protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. RAD23 homolog B, nucleotide excision repair protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus RAD23 homolog B, nucleotide excision repair protein may be involved in the ubiquitin mediated proteolytic pathway in cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Uniprot accession
Molecular weight
43171
Gene ID
Human: 5887; Mouse: 19359; Rat: 298012
Synonyms
RAD23B; UV excision repair protein RAD23 homolog B; HR23B; hHR23B; XP-C repair-complementing complex 58 kDa protein; p58
Research area
Epigenetics and Nuclear Signaling
Target protein
RAD23B
