R-cadherin Polyclonal Antibody

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Home > Product > Antibody > R-cadherin Polyclonal Antibody

R-cadherin Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse

Applications: IHC-p, IF, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse

Applications: IHC-p, IF, ELISA

Product overview

Full product name

R-cadherin Antibody

Code

BT-AP07720

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

CDH4 is a classical cadherin from the cadherin superfamily. The cadherin 4 is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

100281

Gene ID

Human: 1002; Mouse: 12561

Synonyms

CDH4; Cadherin-4; Retinal cadherin; R-CAD; R-cadherin

Research area

Neuroscience

Target protein

CDH4

Recommended dilution

Application	Dilution
IHC	1: 100 - 1: 300
IF	1: 200 - 1: 1000
ELISA	1: 5000

Images

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CDH4 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from COLO205 cells using Cytochrome P450 2D6 antibody.

Immunofluorescence analysis of A549 cells, using CDH4 Antibody. The picture on the right is blocked with the synthesized peptide.

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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