Ref-1 (Acetyl Lys6) Polyclonal Antibody

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Home > Product > Antibody > Ref-1 (Acetyl Lys6) Polyclonal Antibody

Ref-1 (Acetyl Lys6) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-p, ELISA

Product overview

Full product name

Ref-1 (Acetyl Lys6) Antibody

Code

BT-AP07732

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized Acetyl-peptide derived from human APE1 around the Acetylation site of Lys6. AA range:1-50

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells. Splice variants have been found for APEX1; all encode the same protein.

Uniprot accession

Human:;Mouse:;

Molecular weight

35555

Gene ID

Human: 328

Synonyms

APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1

Research area

Epigenetics and Nuclear Signaling

Target protein

APEX1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
IHC-p	1: 100 - 300
ELISA	1: 20000

Images

Western Blot analysis of A549 cells using Acetyl-Ref-1 (K6) Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100

Western blot analysis of lysate from A549 cells, using APE1 (Acetyl-Lys6) Antibody.

Immunohistochemical analysis of paraffin-embedded human-breast, antibody was diluted at 1:100

Western Blot analysis of A549 cells using Acetyl-Ref-1 (K6) Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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