Product overview
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Background
RHEB (Ras homolog enriched in brain) is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
Uniprot accession
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Recommended dilution
Application | Dilution |
---|---|
WB | 1: 500 - 2000 |
ELISA | 1: 10000 - 20000 |
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