Full product name
Ribosomal Protein S6 Antibody
Code
BT-AP07893
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human S6 Ribosomal Protein. AA range:196-245
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage
-20°C for one year
Background
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPS6 encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. 40S ribosomal protein S6 belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Uniprot accession
Molecular weight
28681
Gene ID
Human: 6194; Mouse: 20104; Rat: 1.00911e+008
Synonyms
RPS6; OK/SW-cl.2; 40S ribosomal protein S6; Phosphoprotein NP33
Research area
Epigenetics and Nuclear Signaling
Target protein
RPS6
