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Home > Product > Antibody > SIRT2 Polyclonal Antibody

SIRT2 Polyclonal Antibody

SIRT2 Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: IHC,WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC,WB, ELISA

Product overview

Full product name

SIRT2 Antibody

Code

BT-AP08325

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human SIRT2. AA range:321-370

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

SIRT2 encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of SIRT2.

Uniprot accession

Molecular weight

43182

Gene ID

Human: 22933; Mouse: 64383; Rat: 361532

Synonyms

SIRT2; SIR2L; SIR2L2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; SIR2-like protein 2

Research area

Epigenetics and Nuclear Signaling

Target protein

SIRT2

Recommended dilution

Application Dilution
WB 1: 500 - 1: 2000
ELISA 1: 2000 - 1: 20000
IHC 1: 50 - 1: 300

Images

Western blot analysis of SIRT2 Antibody. The lane on the right is blocked with the SIRT2 peptide.
Western blot analysis of the lysates from RAW264.7cells using SIRT2 antibody.
Western Blot analysis of 293 cells using SIRT2 Polyclonal Antibody diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded human oophoroma. Antibody was diluted at 1:200(4° overnight). Tris-EDTA, pH9.0 was used for antigen retrieval. Secondary antibody was diluted at 1:200(room temperature, 45min).

Protocols

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Product size

Price

  • 20ul

    $108.00

  • 50ul

    $180.00

  • 100ul

    $275.00

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Lead time: Within one week

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