Synapsin-1 Antibody

BT-AP08709

Rabbit

IgG

20ul,50ul,100ul

Polyclonal

Synthesized peptide derived from the Internal region of human Synapsin-1.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

1 mg/ml

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

-20°C for one year

SYN1 (synapsin I) is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in SYN1 may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Human:;Mouse:;Rat:;

74111

Human: 6853; Mouse: 20964

SYN1; Synapsin-1; Brain protein 4.1; Synapsin I

Neuroscience

SYN1