Product overview
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Immunogen
Purification
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Background
TGF-beta receptor type-1 encoded by TGFBR1 forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The TGF-beta receptor type-1 is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.
Uniprot accession
Molecular weight
Gene ID
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Target protein
Recommended dilution
Application | Dilution |
---|---|
WB | 1: 500 - 1: 2000 |
IF | 1: 200 - 1: 1000 |
ELISA | 1: 10000 |
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