XPLN Polyclonal Antibody

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Home > Product > Antibody > XPLN Polyclonal Antibody

XPLN Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-p, ELISA

Product overview

Full product name

XPLN Antibody

Code

BT-AP09619

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

The antiserum was produced against synthesized peptide derived from human ARHGEF3. AA range:456-505

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. ARHGEF3 encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: rHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Uniprot accession

Human:;Mouse:;

Molecular weight

59783

Gene ID

Human: 50650; Mouse: 71704

Synonyms

ARHGEF3; Rho guanine nucleotide exchange factor 3; Exchange factor found in platelets and leukemic and neuronal tissues; XPLN

Research area

Others

Target protein

ARHGEF3

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 20000
IHC-p	1: 50 - 300

Images

Western blot analysis of the lysates from HeLa cells using ARHGEF3 antibody.

Western blot analysis of lysates from COLO cells, using ARHGEF3 Antibody. The lane on the right is blocked with the synthesized peptide.

Western Blot analysis of various cells using XPLN Polyclonal Antibody. Secondary antibody was diluted at 1:20000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

Add to Cart

Lead time: Within one week

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