Full product name
alpha-Skeletal Muscle Actin Antibody
Code
BT-AP09769
Host
Rabbit
Isotype
IgG
Size
20ul,50ul,100ul
Clonality
Polyclonal
Immunogen
Synthetic Peptide of α-Skeletal Muscle Actin
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Concentration
1 mg/ml
Formulation
PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Storage
-20°C for one year
Background
The product (actin, alpha 1, skeletal muscle) encoded by ACTA1 belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in ACTA1 cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Uniprot accession
Molecular weight
42051
Gene ID
Human: 58; Mouse: 11459; Rat: 29437
Synonyms
ACTA1; ACTA; Actin, alpha skeletal muscle; Alpha-actin-1
Research area
Tags & Cell Markers
Target protein
ACTA1
