Product overview
Full product name
Code
Host
Isotype
Size
Clonality
Immunogen
Purification
Concentration
Formulation
Storage
Background
APLP2 encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. Amyloid-like protein 2 is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Uniprot accession
Molecular weight
Gene ID
Synonyms
Research area
Target protein
Recommended dilution
| Application | Dilution |
|---|---|
| IHC | 1: 100 - 1: 300 |
| ELISA | 1: 20000 |
Protocols
Customer reviews and Q&As
