Phospho-Catenin-Beta (S552) Polyclonal Antibody

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Home > Product > Antibody > Phospho-Catenin-Beta (S552) Polyclonal Antibody

Phospho-Catenin-Beta (S552) Polyclonal Antibody

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity:Human, mouse, rat

Applications: WB, ELISA

Product Summary

Size: 20ul,50ul,100ul

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, mouse, rat

Applications: WB, ELISA

Product overview

Full product name

Phospho-Catenin-beta (S552) Antibody

Code

BT-PHS01204

Host

Rabbit

Isotype

IgG

Size

20ul,50ul,100ul

Clonality

Polyclonal

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Catenin-β (phospho Ser552)

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

1 mg/ml

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

-20°C for one year

Background

Catenin beta 1 encoded by CTNNB1 is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. Catenin beta 1 also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, catenin beta 1 binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in CTNNB1 are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for CTNNB1.

Uniprot accession

Human:;Mouse:;Rat:;

Molecular weight

85497

Gene ID

Human: 1499; Mouse: 12387; Rat: 84353

Synonyms

CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin

Research area

Signal Transduction; Neuroscience

Target protein

CTNNB1

Recommended dilution

Application	Dilution
WB	1: 500 - 1: 2000
ELISA	1: 40000

Protocols

> Protocol Booklet

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Datasheet

Product size

Price

20ul

$108.00
50ul

$180.00
100ul

$275.00

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Lead time: Within one week

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