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Home > Product > ELISA Kit > Human Phospholipid Scramblase 1, PLSCR1 ELISA Kit

Human Phospholipid Scramblase 1, PLSCR1 ELISA Kit

Human Phospholipid Scramblase 1, PLSCR1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 8.05ng/L

Detection range: 15-3000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 8.05ng/L

Detection range: 15-3000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

phospholipid scramblase 1

Code

E0955Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

8.05ng/L

Detection range

15-3000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Catalyzes calcium-induced ATP-independent rapid bidirectional and non-specific movement of phospholipids (lipid scrambling or lipid flip-flop) between the inner and outer leaflet of the plasma membrane resulting in collapse of the phospholipid asymmetry which leads to phosphatidylserine externalization on the cell surface (PubMed:9218461, PubMed:8663431, PubMed:10770950, PubMed:9572851, PubMed:9485382, PubMed:18629440, PubMed:23590222, PubMed:24648509, PubMed:24343571, PubMed:32110987, PubMed:23659204, PubMed:29748552). Mediates calcium-dependent phosphatidylserine externalization and apoptosis in neurons via its association with TRPC5 (By similarity). Also exhibits magnesium-dependent nuclease activity against double-stranded DNA and RNA but not single-stranded DNA and can enhance DNA decatenation mediated by TOP2A (PubMed:27206388, PubMed:17567603). Negatively regulates FcR-mediated phagocytosis in differentiated macrophages (PubMed:26745724). May contribute to cytokine-regulated cell proliferation and differentiation (By similarity). May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes (PubMed:15308695). Acts as an attachment receptor for HCV (PubMed:21806988).

UniProt accession

MASS(Da)

35,049

GeneID

5359

Synonyms

Ca(2+-dependent phospholipid scramblase 1;Erythrocyte phospholipid scramblase;Mg(2+-dependent nuclease;MMTRA1B;Phospholipid scramblase 1;PL scramblase 1;PLSCR1

Gene names

PLSCR1

Research area

Microbiology

Target protein

PLSCR1

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E0955Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1600ng/L 2.111 2.046 1.994
1.98
800ng/L 0.988 0.998 0.947
1.009
400ng/L 0.443 0.426 0.375
0.409
200ng/L 0.199 0.246 0.195
0.293
100ng/L 0.139 0.122 0.071
0.106
0ng/L 0.06 0.051 0
0.043

Precision

We measured random samples of E0955Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 525.23 22.69 4.32
Intra-Assay 2 18 1437.92 40.26 2.8
Intra-Assay 3 18 766.75 32.27 4.21

Protocols

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Associated products

  • Size

    Code

    Price

  • 48T

    E0955Hu

    $320.00

  • 96T

    E0955Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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