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Home > Product > ELISA Kit > Human Bone Morphogenetic Protein 6, BMP-6 ELISA Kit

Human Bone Morphogenetic Protein 6, BMP-6 ELISA Kit

Human Bone Morphogenetic Protein 6, BMP-6 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.23mg/L

Detection range: 0.5-150mg/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.23mg/L

Detection range: 0.5-150mg/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Bone Morphogenetic Protein 6

Code

E1480Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.23mg/L

Detection range

0.5-150mg/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Growth factor of the TGF-beta superfamily that plays essential roles in many developmental processes including cartilage and bone formation (PubMed:31019025). Plays also an important role in the regulation of iron metabolism by acting as a ligand for hemojuvelin/HJV (By similarity). Initiates the canonical BMP signaling cascade by associating with type I receptor ACVR1 and type II receptor ACVR2B (PubMed:18070108). In turn, ACVR1 propagates signal by phosphorylating SMAD1/5/8 that travel to the nucleus and act as activators and repressors of transcription of target. Can also signal through non-canonical pathway such as TAZ-Hippo signaling cascade to modulate VEGF signaling by regulating VEGFR2 expression (PubMed:33021694).

UniProt accession

MASS(Da)

57,226

GeneID

654

Synonyms

BMP-6;Bone morphogenetic protein 6;VG-1-R;VG-1-related protein;VGR;VGR1;VGR-1

Gene names

BMP6

Research area

Signal Transduction; Cell Biology; Stem Cells

Target protein

BMP-6

Components

Components Quantity
Pre-coated ELISA plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1480Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
80mg/L 2.309 2.311 2.244
2.312
40mg/L 1.395 1.432 1.365
1.468
20mg/L 0.672 0.744 0.677
0.816
10mg/L 0.485 0.502 0.436
0.52
5mg/L 0.238 0.253 0.187
0.268
0mg/L 0.073 0.066 0
0.06

Precision

We measured random samples of E1480Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 10.93 0.47 4.33
Intra-Assay 2 18 19.26 1.01 5.22
Intra-Assay 3 18 46.6 1.33 2.85

Protocols

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  • Size

    Code

    Price

  • 48T

    E1480Hu

    $320.00

  • 96T

    E1480Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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