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Home > Product > ELISA Kit > Bovine Triggering Receptor Expresses On Myeloid Cells-1, TREM-1 ELISA Kit

Bovine Triggering Receptor Expresses On Myeloid Cells-1, TREM-1 ELISA Kit

Bovine Triggering Receptor Expresses On Myeloid Cells-1, TREM-1 ELISA Kit

Product Summary

Size: 96T,48T

Sensitivity: 2.59ng/L

Detection range: 5-1000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Bovine

Product Summary

Size: 96T,48T

Sensitivity: 2.59ng/L

Detection range: 5-1000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Bovine

Product overview

Full product name

Triggering Receptor Expresses On Myeloid Cells-1

Code

E2257Bo

Assay type

Sandwich

Size

96T,48T

Sensitivity

2.59ng/L

Detection range

5-1000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Bovine

Storage

2-8ºC

Assay time

1h 30m

Background

Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. This cascade promotes the neutrophil- and macrophage-mediated release of proinflammatory cytokines and/or chemokines, as well as their migration and thereby amplifies inflammatory responses that are triggered by bacterial and fungal infections. By also promoting the amplification of inflammatory signals that are initially triggered by Toll-like receptor (TLR) and NOD-like receptor engagement, plays a major role in the pathophysiology of acute and chronic inflammatory diseases of different etiologies including septic shock and atherosclerosis.

UniProt accession

MASS(Da)

25,381

GeneID

404547

Synonyms

CD antigen CD354;TREM 1;TREM1;TREM-1;Triggering receptor expressed on myeloid cells 1

Gene names

TREM1

Research area

Others

Target protein

TREM1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E2257Bo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
640ng/L 2.298 2.222 2.164
2.146
320ng/L 1.821 1.882 1.824
1.943
160ng/L 1.13 1.143 1.085
1.156
80ng/L 0.602 0.657 0.598
0.711
40ng/L 0.378 0.377 0.318
0.376
0ng/L 0.067 0.058 0
0.05

Precision

We measured random samples of E2257Bo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 105.6 4.46 4.2
Intra-Assay 2 18 205.8 8.69 4.2
Intra-Assay 3 18 51.3 2.59 5

Protocols

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  • Size

    Code

    Price

  • 96T

    E2257Bo

    $458.00

  • 48T

    E2257Bo

    $320.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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