Spexin

E3507Hu

Sandwich

48T,96T

4.95ng/L

10-4000ng/L

Serum, plasma, cell culture supernates

Human

2-8ºC

1h 30m

Plays a role as a central modulator of cardiovascular and renal function and nociception. Plays also a role in energy metabolism and storage. Inhibits adrenocortical cell proliferation with minor stimulation on corticosteroid release (By similarity). [Spexin-1]: Acts as a ligand for galanin receptors GALR2 and GALR3 (PubMed: 17284679, PubMed: 24517231). Intracerebroventricular administration of the Peptide induces an increase in arterial blood pressure, a decrease in both heart rate and renal excretion and delayed natriuresis. Intraventricular administration of the Peptide induces antinociceptive activity. Also induces contraction of muscarinic-like stomach smooth muscles. Intraperitoneal administration of the Peptide induces a reduction in food consumption and body weight. Inhibits long chain fatty acid uptake into adipocytes (By similarity). [Spexin-2]: Intracerebroventricular administration of the Peptide induces a decrease in heart rate, but no change in arterial pressure, and an increase in urine flow rate. Intraventricular administration of the Peptide induces antinociceptive activity (By similarity).

13,302

80763

Neuropeptide Q;NPQ;NPQ 53-70;Spexin;Spexin hormone;Spexin-1;Spexin-2;SPX

SPX

Cell Biology

SPX