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Home > Product > ELISA Kit > Human Syntenin-1, SDCBP ELISA Kit

Human Syntenin-1, SDCBP ELISA Kit

Human Syntenin-1, SDCBP ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.02ng/ml

Detection range: 0.05-15ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.02ng/ml

Detection range: 0.05-15ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Syntenin-1

Code

E4148hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.02ng/ml

Detection range

0.05-15ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Multifunctional adapter protein involved in diverse array of functions including trafficking of transmembrane proteins, neuro and immunomodulation, exosome biogenesis, and tumorigenesis (PubMed: 26291527). Positively regulates TGFB1-mediated SMAD2/3 activation and TGFB1-induced epithelial-to-mesenchymal transition (EMT) and cell migration in various cell types. May increase TGFB1 signaling by enhancing cell-surface expression of TGFR1 by preventing the interaction between TGFR1 and CAV1 and subsequent CAV1-dependent internalization and degradation of TGFR1 (PubMed: 25893292). In concert with SDC1/4 and PDCD6IP, regulates exosome biogenesis (PubMed: 22660413). Regulates migration, growth, proliferation, and cell cycle progression in a variety of cancer types (PubMed: 26539120). In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA) (PubMed: 11$498.00|$360.00591). May also play a role in vesicular trafficking (PubMed: 11179419). Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (PubMed: 10230395).

UniProt accession

MASS(Da)

32,444

GeneID

6386

Synonyms

MDA-9;Melanoma differentiation-associated protein 9;Pro-TGF-alpha cytoplasmic domain-interacting protein 18;Scaffold protein Pbp1;SDCBP;Syndecan-binding protein 1;Syntenin-1;TACIP18

Gene names

SDCBP

Research area

Others

Target protein

SDCBP

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E4148hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
8ng/ml 2.301 2.208 2.167
2.116
4ng/ml 1.471 1.451 1.409
1.43
2ng/ml 0.692 0.64 0.598
0.588
1ng/ml 0.366 0.335 0.293
0.304
0.5ng/ml 0.209 0.176 0.134
0.144
0ng/ml 0.057 0.042 0
0.026

Precision

We measured random samples of E4148hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 1.3 0.05 3.7
Intra-Assay 2 18 3 0.13 4.2
Intra-Assay 3 18 3.6 0.11 3

Protocols

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  • Size

    Code

    Price

  • 48T

    E4148hu

    $320.00

  • 96T

    E4148hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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