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Home > Product > ELISA Kit > Human Mothers Against Decapentaplegic Homolog 6, SMAD6 ELISA Kit

Human Mothers Against Decapentaplegic Homolog 6, SMAD6 ELISA Kit

Human Mothers Against Decapentaplegic Homolog 6, SMAD6 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 4.72ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 4.72ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Mothers Against Decapentaplegic Homolog 6

Code

E4442Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

4.72ng/L

Detection range

10-2000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.

UniProt accession

MASS(Da)

53,497

GeneID

4091

Synonyms

hSMAD6;MAD homolog 6;Mothers against decapentaplegic homolog 6;Mothers against DPP homolog 6;SMAD 6;SMAD family member 6;Smad6

Gene names

SMAD6

Research area

Others

Target protein

SMAD6

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E4442Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1200ng/L 2.514 2.459 2.412
2.405
600ng/L 1.441 1.42 1.373
1.4
300ng/L 0.871 0.803 0.756
0.735
150ng/L 0.409 0.441 0.393
0.472
75ng/L 0.231 0.219 0.172
0.207
0ng/L 0.05 0.047 0
0.045

Precision

We measured random samples of E4442Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 119.3 6.53 5.5
Intra-Assay 2 18 608.8 17.06 2.8
Intra-Assay 3 18 359.9 20.13 5.6

Protocols

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E4442Hu

    $320.00

  • 96T

    E4442Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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