Tel:86 021 3100 7137

Publish and get free product : share with us your publications using BT LAB product and get free products.
Home > Product > ELISA Kit > Human Cytochrome P450 26A1, CYP26A1 ELISA Kit

Human Cytochrome P450 26A1, CYP26A1 ELISA Kit

Human Cytochrome P450 26A1, CYP26A1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 4.9ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 4.9ng/L

Detection range: 10-2000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Cytochrome P450 26A1

Code

E5159Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

4.9ng/L

Detection range

10-2000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

A cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed: 22020119, PubMed: 9228017, PubMed: 9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed: 26937021).

UniProt accession

MASS(Da)

56,199

GeneID

1592

Synonyms

CYP26A1;Cytochrome P450 26A1;Cytochrome P450 retinoic acid-inactivating 1;Cytochrome P450RAI;hP450RAI;Retinoic acid 4-hydroxylase;Retinoic acid-metabolizing cytochrome

Gene names

CYP26A1

Research area

Others

Target protein

CYP26A1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E5159Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
1200ng/L 2.206 2.284 2.248
2.362
600ng/L 1.403 1.372 1.335
1.34
300ng/L 0.788 0.697 0.661
0.606
150ng/L 0.379 0.382 0.346
0.385
75ng/L 0.214 0.185 0.149
0.156
0ng/L 0.038 0.036 0
0.035

Precision

We measured random samples of E5159Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 503.1 25.88 5.1
Intra-Assay 2 18 718.4 21.43 3
Intra-Assay 3 18 196.2 8.61 4.4

Protocols

Customer reviews and Q&As

No reviews
No reviews

Associated products

  • Size

    Code

    Price

  • 48T

    E5159Hu

    $320.00

  • 96T

    E5159Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

Newsletter

Sign up

Newsletter

Sign up