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Home > Product > ELISA Kit > Human Integrin Beta-7, ITGB7 ELISA Kit

Human Integrin Beta-7, ITGB7 ELISA Kit

Human Integrin Beta-7, ITGB7 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.051ng/ml

Detection range: 0.1-40ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 0.051ng/ml

Detection range: 0.1-40ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Integrin Beta-7

Code

E5486Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.051ng/ml

Detection range

0.1-40ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is an adhesion molecule that mediates lymphocyte migration and homing to gut-associated lymphoid tissue (GALT). Integrin alpha-4/beta-7 interacts with the cell surface adhesion molecules MADCAM1 which is normally expressed by the vascular endothelium of the gastrointestinal tract. Interacts also with VCAM1 and fibronectin, an extracellular matrix component. It recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Interactions involves the tripeptide L-D-T in MADCAM1, and L-D-V in fibronectin. Binds to HIV-1 gp120, thereby allowing the virus to enter GALT, which is thought to be the major trigger of AIDS disease. Interaction would involve a tripeptide L-D-I in HIV-1 gp120. Integrin alpha-E/beta-7 (HML-1) is a receptor for E-cadherin.

UniProt accession

MASS(Da)

86,903

GeneID

3695

Synonyms

Gut homing receptor beta subunit;Integrin beta-7;ITGB 7;ITGB7

Gene names

ITGB7

Research area

Signal Transduction

Target protein

ITGB7

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E5486Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
24ng/ml 2.316 2.209 2.167
2.102
12ng/ml 1.347 1.401 1.359
1.455
6ng/ml 0.738 0.767 0.725
0.795
3ng/ml 0.402 0.4 0.358
0.398
1.5ng/ml 0.243 0.243 0.201
0.243
0ng/ml 0.043 0.042 0
0.041

Precision

We measured random samples of E5486Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 5.7 0.27 4.6
Intra-Assay 2 18 14.7 0.53 3.6
Intra-Assay 3 18 6.9 0.41 5.9

Protocols

Customer reviews and Q&As

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Associated products

  • Size

    Code

    Price

  • 48T

    E5486Hu

    $320.00

  • 96T

    E5486Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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