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Home > Product > ELISA Kit > Mouse Lectin-like Oxidized Low-density Lipoprotein Receptor 1, OLR1 ELISA Kit

Mouse Lectin-like Oxidized Low-density Lipoprotein Receptor 1, OLR1 ELISA Kit

Mouse Lectin-like Oxidized Low-density Lipoprotein Receptor 1, OLR1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.023ng/ml

Detection range: 0.05-30ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product Summary

Size: 48T,96T

Sensitivity: 0.023ng/ml

Detection range: 0.05-30ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Mouse

Product overview

Full product name

Lectin-Like Oxidized Low-Density Lipoprotein Receptor 1

Code

E1341Mo

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.023ng/ml

Detection range

0.05-30ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Mouse

Storage

2-8ºC

Assay time

1h 30m

Background

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).

UniProt accession

MASS(Da)

41,643

GeneID

108078

Synonyms

Lectin-like oxidized LDL receptor 1;Lectin-like oxLDL receptor 1;Lectin-type oxidized LDL receptor 1;LOX-1;OLR 1;OLR1;Oxidized low-density lipoprotein receptor 1;Oxidized low-density lipoprotein receptor 1, soluble form;Ox-LDL receptor 1;

Gene names

OLR1

Research area

Cardiovascular

Target protein

OLR1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1341Mo are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
16ng/ml 2.09 2.113 2.091
2.135
8ng/ml 1.449 1.47 1.448
1.491
4ng/ml 0.674 0.713 0.692
0.753
2ng/ml 0.316 0.371 0.349
0.425
1ng/ml 0.123 0.127 0.105
0.132
0ng/ml 0.022 0.022 0
0.021

Precision

We measured random samples of E1341Mo within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 7.5 0.21 2.7
Intra-Assay 2 18 6.3 0.35 5.6
Intra-Assay 3 18 2.1 0.06 2.8

Protocols

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  • Size

    Code

    Price

  • 48T

    E1341Mo

    $320.00

  • 96T

    E1341Mo

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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