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Home > Product > ELISA Kit > Rat Oxidized Low-density Lipoprotein Receptor 1, LOX-1 ELISA Kit

Rat Oxidized Low-density Lipoprotein Receptor 1, LOX-1 ELISA Kit

Rat Oxidized Low-density Lipoprotein Receptor 1, LOX-1 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 0.32ng/ml

Detection range: 0.5-60ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat

Product Summary

Size: 48T,96T

Sensitivity: 0.32ng/ml

Detection range: 0.5-60ng/ml

Sample type: Serum, plasma, cell culture supernates

Reactive with: Rat

Product overview

Full product name

Oxidized Low-Density Lipoprotein Receptor 1

Code

E1064Ra

Assay type

Sandwich

Size

48T,96T

Sensitivity

0.32ng/ml

Detection range

0.5-60ng/ml

Sample type

Serum, plasma, cell culture supernates

Species

Rat

Storage

2-8ºC

Assay time

1h 30m

Background

Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

UniProt accession

MASS(Da)

41,890

GeneID

140914

Synonyms

Lectin-like oxidized LDL receptor 1;Lectin-like oxLDL receptor 1;Lectin-type oxidized LDL receptor 1;LOX-1;OLR 1;OLR1;Oxidized low-density lipoprotein receptor 1;Oxidized low-density lipoprotein receptor 1, soluble form;Ox-LDL receptor 1;

Gene names

OLR1

Research area

Cardiovascular

Target protein

OLR1

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E1064Ra are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
32ng/ml 2.369 2.249 2.219
2.128
16ng/ml 1.357 1.269 1.239
1.181
8ng/ml 0.736 0.708 0.678
0.68
4ng/ml 0.498 0.471 0.441
0.443
2ng/ml 0.205 0.199 0.169
0.193
0ng/ml 0.034 0.03 0
0.026

Precision

We measured random samples of E1064Ra within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 15.2 0.71 4.7
Intra-Assay 2 18 15.4 0.52 3.4
Intra-Assay 3 18 8.1 0.59 7.2

Protocols

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  • Size

    Code

    Price

  • 48T

    E1064Ra

    $320.00

  • 96T

    E1064Ra

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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