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Home > Product > ELISA Kit > Human Presenilin 2, PS-2 ELISA Kit

Human Presenilin 2, PS-2 ELISA Kit

Human Presenilin 2, PS-2 ELISA Kit

Product Summary

Size: 48T,96T

Sensitivity: 2.47ng/L

Detection range: 5-1000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product Summary

Size: 48T,96T

Sensitivity: 2.47ng/L

Detection range: 5-1000ng/L

Sample type: Serum, plasma, cell culture supernates

Reactive with: Human

Product overview

Full product name

Presenilin 2

Code

E0980Hu

Assay type

Sandwich

Size

48T,96T

Sensitivity

2.47ng/L

Detection range

5-1000ng/L

Sample type

Serum, plasma, cell culture supernates

Species

Human

Storage

2-8ºC

Assay time

1h 30m

Background

Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. May function in the cytoplasmic partitioning of proteins. The holoprotein functions as a calcium-leak Channel that allows the passive movement of calcium from endoplasmic reticulum to cytosol and is involved in calcium homeostasis (PubMed: 16959576). Is a regulator of mitochondrion-endoplasmic reticulum membrane tethering and modulates calcium ions shuttling between ER and mitochondria (PubMed: 21285369).

UniProt accession

MASS(Da)

50,140

GeneID

5664

Synonyms

AD3LP;AD5;E5-1;Presenilin-2;Presenilin-2 CTF subunit;Presenilin-2 NTF subunit;PS-2;PSEN 2;PSEN2;STM-2

Gene names

PSEN2

Research area

Neuroscience

Target protein

PSEN2

Components

Components Quantity
Pre-coated ELISA Plate 12 * 8 well strips x1
Standard solution 0.5ml x1
Standard diluent 3ml x1
Streptavidin-HRP 6ml x1
Stop solution 6ml x1
Substrate solution A 6ml x1
Substrate solution B 6ml x1
Wash buffer concentrate (25x) 20ml x1
Biotinylated antibody 1ml x1

Protocol data

These standard curves of E0980Hu are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

Concentration O.D. Average Corrected
640ng/L 1.705 1.766 1.707
1.826
320ng/L 1.105 1.006 0.948
0.907
160ng/L 0.539 0.574 0.515
0.609
80ng/L 0.267 0.222 0.164
0.177
40ng/L 0.109 0.128 0.069
0.147
0ng/L 0.06 0.059 0
0.057

Precision

We measured random samples of E0980Hu within the same batch/lot to ensure the consistency of the kits' performances.

Intra/Inter-Assay Sample n Mean Standard Deviation CV%
Intra-Assay 1 18 659.6 34.48 5.2
Intra-Assay 2 18 397.2 21.72 5.5
Intra-Assay 3 18 123.1 5.38 4.4

Protocols

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  • Size

    Code

    Price

  • 48T

    E0980Hu

    $320.00

  • 96T

    E0980Hu

    $458.00

Add to Cart

Lead time: Within two weeks

We are continuously updating our ELISA Kit catalog with advanced verified products. If you can not download the datasheet please send your request of our latest datasheet.

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