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Home > Product > Antibody > CD45 Monoclonal Antibody

CD45 Monoclonal Antibody

CD45 Monoclonal Antibody

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity:Human

Applications: WB, IHC-p, IF, ELISA

Product Summary

Size: 50ul,100ul

Clonality: Monoclonal

Host: Mouse

Reactivity: Human

Applications: WB, IHC-p, IF, ELISA

Product overview

Full product name

Receptor-type tyrosine-protein phosphatase C

Code

BT-MCA0308

Host

Mouse

Isotype

IgG

Size

50ul,100ul

Clonality

Monoclonal

Immunogen

Purified recombinant fragment of CD45 expressed in E. Coli.

Purification

Affinity purification

Concentration

1 mg/ml

Formulation

Ascitic fluid containing 0.03% sodium azide,0.5% BSA, 50%glycerol.

Storage

-20°C for one year

Background

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which enc

Uniprot accession

Molecular weight

N/A

Gene ID

Human: 5788

Synonyms

PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45

Research area

Immunology; Stem cells; Cardiovascular; Signal transduction; Neuroscience

Target protein

PTPRC

Recommended dilution

Application Dilution
ELISA 1:10000
IHC 1:200 - 1:1000
WB 1:500 - 1:2000

Images

Western Blot analysis using CD45 Monoclonal antibody against truncated CD45 recombinant protein (1).
Immunohistochemistry analysis of paraffin-embedded human lymph node tissue, showing membrane and cytoplasmic localization with DAB staining using CD45 Monoclonal antibody.

Protocols

Customer reviews and Q&As

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Product size

Price

  • 50ul

    $180.00

  • 100ul

    $300.00

Add to Cart

Lead time: Within one week

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